08:30–09:30 | Registration | |
09:30 | Opening Hubert Löwenheim | |
09:30–09:40 | Welcome Boris Palmer (Lord Mayor of Tübingen) | |
09:40–09:50 | Welcome Hendrik Rosewich (Speaker, Centre for Rare Diseases, Tübingen) | |
09:50–10:00 | Welcome and Introduction to the Symposium, Hubert Löwenheim | |
10:00 | Session 01- Advanced Genetic Diagnostics, Drug Delivery and Drug Therapy Moderators: Ronald Pennings, Anke Tropitzsch | |
10:00–10:30 | Eliot Shearer (Harvard University) “Diagnostic Evaluation for Hearing Loss in the Era of Gene Therapy” | |
10:30–10:50 | Anil Lalwani (Columbia University) "Microneedle-Mediated Safe and Precise Inner Ear Delivery" | |
10:50–11:10 | Christoph Arnoldner (Vienna University) "Drug Delivery Studies in the Large Animal Model Pig" | |
11:10–11:30 | Jonathan Kil (Sound Pharmaceuticals) “Drug Development and Clinical Trials" | |
11:30–12:00 | Round table Moderators: Ronald Pennings, Anke Tropitzsch Panelists: Eliot Shearer, Anil Lalwani, Christoph Arnoldner, Jonathan Kil | |
12:00 | Lunch | |
13:00 | Session 02 - Current Gene Therapy Trials Moderators: Hinrich Staeker, Hubert Löwenheim | |
13:00–13:20 | Géraldine Honnet (Sensorion) "SENS-501 Gene Therapy in Young Children with Severe to Profound Hearing Loss Due to Otoferlin Mutations" | |
13:20–13:40 | Carleton E. Corrales (Regeneron) “Safety and Efficacy of DB-OTO Gene Therapy in Children with Profound Deafness due to Otoferlin Variants: Data from the CHORD Phase 1/2 Open-label Trial” | |
13:40–14:00 | Aaron Tward (Akouos/Lilly) "Clinical Development of AK-OTOF Gene Therapy for OTOF-mediated Hearing Loss: Preliminary Results" | |
14:00–14:20 | Yuxin Chen (Eye & ENT Hospital, Fudan University) "Gene Therapy vs Cochlear Implantation in Restoring Hearing Function and Speech Perception for Congenital Deafness Individuals" | |
14:20–15:00 | Round table Moderators: Hinrich Staecker, Hubert Löwenheim Panelists: Géraldine Honnet, Carleton E. Corrales, Aaron Tward, Yuxin Chen | |
15:00 | Break | |
15:30 | Session 03 - Stem Cell Therapies & Organoids Moderators: Athanasia Warnecke, Thore Schade-Mann | |
15:30–15:50 | Heiko Locher (Leiden University Medical Center) "Mapping and Modeling the Human Inner Ear: RNA Atlases, Organoids, and Clinical Applications" | |
15:50–16:10 | Pascal Senn (University Hospital of Geneva) "From Regeneration of Auditory Neurons to Drug Screening" | |
16:10–16:30 | Marcelo Rivolta (Rinri Therapeutics) “Recent Advances in the Development of a Pluripotent Stem-Cell Based Therapy for the Treatment of Hearing Loss” | |
16:30–17:00 | Round Table Moderators: Athanasia Warnecke, Thore Schade-Mann Panelists: Heiko Locher, Pasacal Senn, Marcelo Rivolta | |
17:00–19:00 | Welcome reception at the Rooftop of the congress venue |
Please click here for the detailed programme.